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Effect of Flow Rate on In Vitro Aerodynamic Performance of NEXThaler(®) in Comparison with Diskus(®) and Turbohaler(®) Dry Powder Inhalers.

J Aerosol Med Pulm Drug Deliv · 2016 · PMC4841907 · PMID 26355743

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showed a trendno p-value reported
( 32 ) A study conducted in 10 asthmatic subjects showed a trend towards a reduced bronchodilator response at the lower flow rate, even if this did not reach statistical significance.

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