Susceptibility to Ticks and Lyme Disease Spirochetes Is Not Affected in Mice Coinfected with Nematodes.

Although the difference was not significant ( P = 0.15), the number of Heligmosomoides organisms showed a negative trend versus the number of ticks, with every nematode reducing the number of ticks by 2.4% (95% CI, −6.6% [decrease] to +0.17% [increase]).

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An observed trend for decreased local and systemic Th1 reactivity against B. afzelii in coinfected mice did not result in a higher spirochete burden, nor did it facilitate bacterial dissemination or induce signs of immunopathology.

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Only a trend for a negative influence of the number of Heligmosomoides organisms on the tick count was observed, although it did not reach statistical significance.

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