Serum CRP and fecal calprotectin both showed a trend towards higher concentrations in the inflamed population compared to uninflamed and healthy controls (CRP data only for the latter group), but the variability was considerable and no statistically significant differences were observed.
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Validation and Optimization of an Ex Vivo Assay of Intestinal Mucosal Biopsies in Crohn's Disease: Reflects Inflammation and Drug Effects.
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The sentences
When biopsies from non-inflamed patients were compared to those from healthy controls, all 5 cytokines showed a strong trend towards increased levels for the former group, although the difference did not reach significance.