However there does not appear to be a clear trend in any of these parameters, and the limited number of studies reporting these measures precludes statistical analysis.
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Meta-Analysis of Serum Insulin-Like Growth Factor 1 in Alzheimer's Disease.
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The sentences
While eight out of the nine studies included in this meta-analysis detected a statistically significant increase or decrease in serum levels of IGF-1 in Alzheimer’s disease subjects, the analysis as a whole did not show a significant trend in either direction.