Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives.

J Pharmacol Exp Ther · 2016 · PMC4885513 · PMID 27190170

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did not reach statistical significanceP > 0.05actually significant

a strong trendno p-value reported

2E ) compared with VA; in addition, a strong trend toward more pronounced I GABA enhancement of α 1 β 2 γ 2S channels by VA-MA was observed; however, this effect did not reach statistical significance (VA-MA: E max = 917 ± 36%, n = 3, P > 0.05, Fig. 2E ).

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