Critical role for the mediodorsal thalamus in permitting rapid reward-guided updating in stochastic reward environments.

The interaction of lesion group x surgery for the subjective values (V1 RL ) showed a trend for significance (p=0.054) ( Figure 3—figure supplement 1 ).

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There was also a strong trend towards a 4-way interaction between lesion group, surgery, previous outcome and pre- or post-reversal ( F 1,8 = 5.12, p=0.054); switch rates selectively increased in the MDmc group after surgery and this was particularly pronounced after a reward (average post-surgery increase in switch probability: after reward 0.15 ± 0.07, post-hoc tests: p=0.051; after no reward: 0.08 ± 0.06, p=0.23).

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