The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria.

Sci Rep · 2016 · PMC4891778 · PMID 27255786

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

Among SM children, those who had a second SM episode showed a trend toward lower plasma sEPCR both at initial admission and at 6-month follow-up compared to those without repeated SM ( P = 0.06 for both).

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did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

2a ), but the latter comparison did not reach statistical significance ( P = 0.07) likely because of the small sample size of children with UM.

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