Intrathecal T-cell clonal expansions in patients with multiple sclerosis.

Ann Clin Transl Neurol · 2016 · PMC4891996 · PMID 27547770

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significanceP = 0.08so close (0.05 < p ≤ 0.1)

Higher numbers of hyperexpanded clonotypes were observed in the CSF of MS patients relative to PB, which did not reach statistical significance most likely due to a single outlier ( P = 0.08), whereas this trend was not observed in IIH controls (Fig. 6 B).

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a clear trendno p-value reported

6 A), there was a clear trend toward a higher number of hyperexpanded clonotypes in the MS patients’ CSF compared with that in the PB; and the number was significantly higher than that in controls (Fig. 6 B).

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