Also, the meta-analysis revealed a strong trend in the proportion that deteriorated between placebo and IVIG-treated patients ( Table 4 ).
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Safety and effectiveness assessment of intravenous immunoglobulin in the treatment of relapsing-remitting multiple sclerosis: A meta-analysis.
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There were no evidence of heterogeneity among the studies (p= 0.860, χ 2 = 2.57, I 2 =0.0%). Four trials showed a trend towards a reduction in EDSS score during the IVIG treatment when compared to the baseline.