Plasma Osteopontin Levels and Adverse Cardiovascular Outcomes in the PEACE Trial.

PLoS One · 2016 · PMC4902195 · PMID 27284698

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0800

boldest claim

The sentences

approached significanceP = 0.06so close (0.05 < p ≤ 0.1)

An interaction term approached significance ( P = 0.06) in the full model, but the corresponding main effect of treatment was noticeably not associated in this modeling scenario ( P = 0.16).

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near significanceP = 0.06so close (0.05 < p ≤ 0.1)

Please remark how the continuous NRI achieved near significance (0.085; P = 0.06), providing further evidence of the value of OPN when estimating risk for the composite event.

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approaching significanceP = 0.08so close (0.05 < p ≤ 0.1)

While Ln OPN was only approaching significance in the full model [HR (95% CI) = 1.20 (0.98, 1.48); P = 0.08)], it was highly noteworthy with respect to our primary hypothesis that Ln OPN’s association was statistically significant after removing the unassociated covariates [HR (95% CI) = 1.24 (1.01, 1.52); P = 0.04)].

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