Effects of the combinations of amlodipine/valsartan versus losartan/hydrochlorothiazide on left ventricular hypertrophy as determined with magnetic resonance imaging in patients with hypertension.

J Drug Assess · 2012 · PMC4980731 · PMID 27536421

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did not reach statistical significanceno p-value reported

baseline but the difference between groups did not reach statistical significance.

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showed a trendno p-value reported

Secondary endpoints Mean IVS was significantly reduced by both treatments (A/V −1.1 mm; L/H −0.6 mm), and the resulting difference between groups in favour of A/V in the ITT population was significant for the absolute change (−0.7 mm, 95% CI −1.3; −0.1), and showed a trend for significance for the relative change (−4.1%; 95% CI −8.1; 0.0).

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