Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function.

Where univariate models of the imaging measures, controlling for age and sex, were nominally significant ( P <0.05), the analyses were repeated using mixed linear models implemented in ASReml-R ( www.vsni.co.uk/software/asreml ), fitting the inverse relationship matrix as a random effect, allowing us to control for familial structure.

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Reaction time in the verbal WM ‘N-back’ task showed a trend for a main effect of WM load (F(2,36)=2.571, P= 0.09), but no significant effect of the group (F(1,18)=0.018, P= 0.89), or the group×WM load interaction (F(2,36)=1.537, P= 0.23).

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