Gray Matter Involvement in Radiologically Isolated Syndrome.

Medicine (Baltimore) · 2016 · PMC4998546 · PMID 27043685

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.1200

boldest claim

The sentences

a considerable trend toward significanceP = 0.054so close (0.05 < p ≤ 0.1)

A considerable trend toward significance in total brain volume was observed in RIS patients compared with healthy controls (1528 ± 64.40 vs 1575 ± 36.82, P = 0.054).

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did not reach statistical significanceP = 0.12not close (p > 0.1)

A trend toward lower normalized total brain and cortical volumes was observed in RIS patients who failed in at least one cognitive test compared with those without cognitive impairment, but these differences did not reach statistical significance ( P = 0.12 and 0.33, respectively).

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near-significantno p-value reported

Normalized cortical volume was significantly lower on RIS group compared with healthy controls (673 ± 27.07 vs 641 ± 35.88 (cm 3 × 10 3 ), Tukey P test = 0.009), whereas near-significant difference was observed between CIS and healthy control groups (648 ± 27.34 vs 673 ± 27.07 (cm 3 × 10 3 ), Tukey P test = 0.057).

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