There was significant heterogeneity between the studies on the effects of PUFA supplementation on ALT ( χ 2 = 17.18, P = 0.02, I 2 = 59%), with the random effects model, and the pooled MD for ALT showed a trend toward PUFA therapy versus control on ALT but did not reach statistical significance (MD = −4.97, 95% CI: −11.14 to 1.20, P = 0.11) ( Figure 3 ).
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Effects of Omega-3 Fatty Acid in Nonalcoholic Fatty Liver Disease: A Meta-Analysis.
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