Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese mice.

In cases where means did not reach statistical significance by ANOVA, but changes were pronounced, t ‐tests were performed with P values indicated on the corresponding data plots.

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Total islet areas were unaffected by didemnin B treatment, but showed a trend toward being decreased in calorie‐restricted mice (Fig. 7 B).

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