The five year overall and disease specific survival was worse for patients with L1CAM expression, but it did not reach statistical significance (49.4% vs 61.3%, log rank P =0.074 and 70% vs 80%, log rank P = 0.159) (Table 6 ).
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Prognostic value and clinicopathologic characteristics of L1 cell adhesion molecule (L1CAM) in a large series of vulvar squamous cell carcinomas.
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Patients with L1CAM positive tumours showed a trend towards increased risk of dying, with a hazard ratio of 1.58 (95% CI 0.79 – 3.19) for disease specific survival and 1.48 (95% CI 0.93 – 2.35) for overall survival, these hazard ratios however did not reach statistical significance ( Supplementary Table S1 ).