All mice adoptively transferred with CD4 + T cells showed highly significant control of tumor growth compared with controls that received no cells (Figure 1B ).
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Collaboration between tumor-specific CD4+ T cells and B cells in anti-cancer immunity.
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Mice that received T plus B cells compared with T cells alone showed a trend towards reduced ability to control tumor growth after day 50, although the effect failed to reach statistical significance ( p = 0.0516) (Figure 1B ).