Impaired Subset Progression and Polyfunctionality of T Cells in Mice Exposed to Methamphetamine during Chronic LCMV Infection.

METH shifted the IFN-γ–granzyme B correlation to a negative trend in the CD4 T cells; the CD8 T cells remained negatively correlated for these two markers.

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While METH increased the percentage of both CD4 and T cells co-expressing these cytokines, the results did not reach statistical significance.

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While TNF-α was negatively correlated in CD4 T cells, CD8 T cells showed a positive trend.

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