On the other hand, EE-EGCG–treated WT mice also showed a trend toward an enlargement of VGAT puncta size in CA1 (data not shown; Table 6 ), leading to a decreased VGLUT1/VGAT percentage of area occupied ( Fig. 6 D ; Table 6 ) in comparison to untreated WT mice.
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Combined Treatment With Environmental Enrichment and (-)-Epigallocatechin-3-Gallate Ameliorates Learning Deficits and Hippocampal Alterations in a Mouse Model of Down Syndrome.
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The mean difference in these parameters between EE-EGCG–treated and untreated Ts65Dn mice was fairly large; however, it did not reach statistical significance, possibly because of high variability of the data ( Fig. 1 A , E , F ; Table 1 ).