Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex.

J Neurogastroenterol Motil · 2017 · PMC5216644 · PMID 27829577

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantP < 0.001actually significant

Two-way ANOVA showed highly significant differences by treatment group (F [2, 40] =10.5, P < 0.001) and sex (F [1, 40] =12, P < 0.01).

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did not reach statistical significanceP = 0.050actually significant

showed a trendP = 0.050actually significant

Limited Nesting Stress from Post-natal Days 2–10 Increased Plasma Corticosterone Levels in Pups at Weaning In PND21 males, plasma corticosterone values showed a trend to be higher in LNS group compared to CTL which did not reach statistical significance (4.0 ± 0.4 μg/dL vs 2.4 ± 0.7 μg/dL, P = 0.050, n = 8–9) ( Fig. 1A ).

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