Protection Elicited by Nasal Immunization with Recombinant Pneumococcal Surface Protein A (rPspA) Adjuvanted with Whole-Cell Pertussis Vaccine (wP) against Co-Colonization of Mice with Streptococcus pneumoniae.

PLoS One · 2017 · PMC5245875 · PMID 28103277

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showed a trendno p-value reported

Once again, immunization with a mixture of rPspA1+rPspA4+wP showed a trend towards greater reduction in colonization with both strains when compared with a single antigen.

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did not reach statistical significanceno p-value reported

We now observed a slight increase in levels of IL-17A in NW samples of mice inoculated with wP and rPspA+wP, but it did not reach statistical significance (data not shown).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.