highly significantP value of < .01
Differences were considered significant at a P value of less than .05, highly significant at a P value of < .01, and very highly significant at a P value of less than .001.
Differences were considered significant at a P value of less than .05, highly significant at a P value of < .01, and very highly significant at a P value of less than .001.
Although not significant, the mRNA expression of OGR1 showed a clear trend to an increase 1 week after hypoxia in CD and UC patients when compared with HVs ( Figure 1 B ).
Conversely, MM6 cells exposed to hypoxia at pH 7.7, 7.3, and 6.8 showed a trend toward a decreased TDAG8 expression compared with the respective normoxic conditions ( Figure 4 B ).