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Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells.

PLoS One · 2017 · PMC5291532 · PMID 28158203

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showed a trendno p-value reported
SM also showed a trend towards modifying CD4+ T cell memory subsets from HIV+ subjects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.