Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab.

J Transl Med · 2017 · PMC5319167 · PMID 28222797

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showed a trendno p-value reported

Clear differences in RFS were noted based on cytokine level clustering both at baseline and at week 6: Patients whose PBMCs secreted more cytokines in response to NY-ESO-1 showed a trend towards better RFS.

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did not reach statistical significanceno p-value reported

While this did not reach statistical significance, there was a sharp trend towards improved RFS in cluster 1, where 5 of 7 patients had good RFS, whereas in cluster 2, 5 of 6 patients had poor RFS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.