Tumor Budding, uPA, and PAI-1 in Colorectal Cancer: Update of a Prospective Study.

Gastroenterol Res Pract · 2017 · PMC5327786 · PMID 28286517

Europe PMC DOI

hedged sentences

0.0910

closest p · 1.8× alpha

0.1530

boldest claim

The sentences

showed a trendP = 0.091so close (0.05 < p ≤ 0.1)

PAI-1 showed a trend towards reduced cancer specific survival in PAI-1 high-grade cases (68 versus 83 months; P = 0.091).

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a nonsignificant trendP = 0.153not close (p > 0.1)

Additionally, a nonsignificant trend towards higher PAI-1 levels was found in metastatic disease ( P = 0.153) ( Figure 3(h) ), whereas the uPA levels showed no significant differences between localized and metastatic disease ( Figure 3(g) ).

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a clear trendno p-value reported

However, a clear trend towards adverse outcome was found for PAI-1.

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marginal significanceno p-value reported

However, in our validation set, we only found a weak correlation between budding and PAI-1 with marginal significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.