Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions.

Oncotarget · 2016 · PMC5341998 · PMID 27716617

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

MMP-13 IRS increased significantly in low grade adenomas compared to healthy controls ( p = 0.008), in high grade adenoma compared to low grade adenoma ( p < 0.001), whereas the further increase in carcinomas did not reach statistical significance ( p = 0.059; Figure 2B ).

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showed a trendno p-value reported

A high MMP-13 staining score showed a trend towards poorer survival [ 7 ] and a high MMP-13 expression level is associated with a high rate of liver metastasis [ 9 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.