There was a highly significant difference between A9- and A10-like dopamine neuron populations in the grafts [within-subject factor – Staining, F (1,60) = 111.48, p < 0.001] influenced by both the host environment [Transplantation Site, F (3,60) = 14.19, p < 0.001] and the VM age [Donor Age, F (1,60) = 31.59, p < 0.001; Transplantation Site × Donor Age, F (3,60) = 4.48, p < 0.01].
Similarly, a higher percentage of A10-like dopamine neurons was found in the periphery of E14 grafts in N.Acc and PFC than in the dSTR or HPC but the differences failed to reach statistical significance. 4.
The yield of A10-like dopamine neurons in E14 grafts in N.Acc was higher than in other brain regions but this did not reach statistical significance [ Fig. 5 J; simple effect of Transplantation Site for E14 group, F (3,60) = 0.85, n.s.].