showed a trendP =0.07
DDAH1 in kidney showed a trend toward decreased ( P =0.07, n =8 vs 5/group) expression in Akita offspring at 6 weeks, while DDAH2 was not different from control kidney.
DDAH1 in kidney showed a trend toward decreased ( P =0.07, n =8 vs 5/group) expression in Akita offspring at 6 weeks, while DDAH2 was not different from control kidney.
In addition, the expression of the ADMA-metabolizing enzyme DDAH1 in kidney was lower in 6-weeks-old Akita offspring compared with control, although, likely due to low numbers of tissues studied, this difference between groups did not reach statistical significance.