However, the majority of them failed to reach statistical significance.
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Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese.
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Merely marginally significant evidence for the association between rs719725 and CRA risk was observed in a case-control study [ 47 ].
These variants did not reach statistical significance of GWAS possibly due to insufficient sample size, with only 1,049 colorectal cancer cases and 1,315 controls in the GWAS stage.