The fate of patients with intermittent claudication in the 21st century revisited - results from the CAVASIC Study.

Overall mortality, cardio- and cerebrovascular morbidity and mortality in patients with and without prevalent cardiovascular disease First, the age-adjusted Cox regression model on overall mortality did not violate the proportional hazards assumption: PAD patients with concomitant CVD showed a clear trend for a higher risk to die from all causes compared to those PAD patients without CVD, however, without reaching statistical significance: HR 1.66, 95%CI (0.89–3.10), p = 0.11.

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This, however, did not reach statistical significance which was most probably caused by limited statistical power.

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