Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson's disease patients.

Although a lack of tryptophan and serotonin is a hallmark of PD, this finding did not reach statistical significance after multiple testing correction (all p < 0.05, q > 0.1) and needs further exploration in a larger cohort.

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eligens ) showed a trend towards correlation with disease severity (n.s.).

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