This highlighted a prominent role for one particular taxon, an unclassified Peptostreptococcaceae , which had a trend toward significant correlation ( p = .058) with the right inferior segment of the circular sulcus though it fell short of significance as compared to the metagene encoding 4-hydroxybutyrate dehydrogenase ( p = .008) (Fig. 5b ).
Although overweight status (BMI >25.0) was not significantly different between the two IBS clusters, IBS1 [m(sd), 25.52 (5.68)] showed a trend ( t (27) = 1,99, p = .057) toward greater BMI compared to HC-like IBS [20.99 (6.51)], Hedge’s effect size g (Cohen’s d corrected for small sample sizes) = .74.
Even though we observed trends for higher BMI and higher plant-derived fat intake in the IBS1 group, these differences did not reach statistical significance.