Barely Significant
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C-C motif-ligand 2 inhibition with emapticap pegol (NOX-E36) in type 2 diabetic patients with albuminuria.

Nephrol Dial Transplant · 2017 · PMC5410979 · PMID 28186566

2
hedged sentences
0.1460
closest p · 2.9× alpha
0.1460
boldest claim

The sentences

showed a trendP = 0.146not close (p > 0.1)
The difference between the two groups showed a trend towards improvement (P = 0.146).

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a clear trendno p-value reported
When comparing the ITT and post hoc analysis data, it is obvious that (i) qualitatively, both sets show a virtually identical time course of ACR—the specific beneficial effect sets in 2 months after start of treatment, improves further until end of treatment and is maintained after cessation of dosing; (ii) quantitatively, the placebo-corrected effect of emapticap on ACR is most pronounced and statistically significant in the post hoc analysis, and maintained at least as a clear trend in the ITT population; and (iii) the improved separation in ACR between emapticap and placebo in the post hoc analysis is mainly due to reduced background noise in the placebo group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.