Use of metformin and survival of diabetic women with breast cancer.

Although their findings did not reach statistical significance, Lega et al ., reported a possible 9% reduction in breast cancer-specific mortality per additional year of cumulative metformin use [ 17 ], suggesting the beneficial effect of metformin use may be dependent on duration of treatment.

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However, the differences between prescription categories failed to reach statistical significance for any direct comparisons.

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