A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma.

When markers between these two survival groups were compared, we found that tumors associated with poor survival had a strong trend towards having higher total c-MET level compared to those with better survival ( p = 0.05), resonating previous report showing c-MET to be frequently overexpressed and represents an independent poor prognostic factor in resected PDAC patients [ 18 , 19 ].

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Of the 57 non-operable patients, patients with locally-advanced (N = 37) or metastatic disease (N = 20) had a median OS of 9.7 and 6.7 months respectively, which did not reach statistical significance (Wilcoxon P = 0.36) probably due to small sample size and the inherent aggressive nature of this disease.

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