A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis.

PLoS Negl Trop Dis · 2017 · PMC5435357 · PMID 28475641

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

In addition, the patients with bacteremia also showed a trend toward higher levels of TNF-α in plasma (median 3.65, IQR 0–7.28) compared with those with no bacteremia (median 0.53, IQR 0–4.51, P = 0.06).

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a strong trendno p-value reported

Interestingly, we also found a strong trend towards higher plasma TNF-α levels and the presence of bacteremia.

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