7d ); however the data did not reach statistical significance due to low KLF2 mRNA abundance in activated B cells 15 , 34 .
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Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.
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Pairwise comparison with genes differentially expressed between wildtype Fo and MZ B cells indicated that Fo B cells from Rosa26 GFPZFP36L1 CD23 cre/+ mice showed a trend towards increased expression of genes preferentially expressed in MZ B cells ( Fig. 5b and Supplementary table 5 ) and reduced expression of genes characteristically expressed in Fo B cells ( Fig. 5b and Supplementary table 5 ).