Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.

However, GATA4 and HNF4α showed a trend toward higher expression in the HDF‐derived clones.

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In line with this, our PHH‐derived iPSCs do appear to show a significant trend (Supporting Information Fig.

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The data demonstrated a nonsignificant trend pointing toward PHH‐derived clones having slightly higher, but nonsignificantly different, albumin secretion in two of the three donors (Fig. 5 A).

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