JSLE sera augmented MCP-1 secretion (552.8 pg/ml; 197.4-1186) compared to healthy control sera (271.8 pg/ml; 258.4-1524) but this increase did not reach statistical significance.
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Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part three : Genoa, Italy. 28 September – 01 October 2016
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The sentences
The IgG isotypes of both ACA and aβ 2 GP1 antibodies were highest in infants and showed a decreasing trend with increasing age.
The results didn’t indicate any statistically significant abundance of miRs with described role in expression of examined genes, nor hypermethylation of their promotor sites, but there was a clear trend of higher methylation of PTPN12 in jSpA patients, while lack of statistical significance could be attributed to small number of study participants.