Influence of West African Ethnicity and Gender on Beta-Cell Function and Insulin Sensitivity in Essential Hypertensives Treated with Hydrochlorothiazide and Hydrochlorothiazide-lisinopril Combination.

J Pharmacol Pharmacother · 2017 · PMC5497402 · PMID 28706401

Europe PMC DOI

hedged sentences

0.5380

closest p · 10.8× alpha

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boldest claim

The sentences

did not reach statistical significanceP = 0.538not close (p > 0.1)

Results: After 12 weeks, mean delta HOMA-IR (and %) was higher in the HCT monotherapy group; although, this change did not reach statistical significance in both groups −0.1 ± 7.1, P = 0.538 (HCT) and 0.6 ± 4.2 P = 0.913 (HCT + Lis); an insignificant increase was observed in FPG and serum insulin in both groups, whereas serum potassium decreased in similar fashion.

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a clear trendno p-value reported

There was a clear trend to Lis mitigation of IR following HCT.

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