Stability of Proteins in Dried Blood Spot Biobanks.

The levels of all proteins (regardless of storage-time) with nominally significant ( p < 0.05) contributions were subsequently adjusted for age and/or plasma/serum by removing the contribution using the beta (β)-coefficient(s) from the linear models.

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For some proteins, no decreases could be detected even after 30 years of storage, but for several proteins a clear trend toward decreasing levels was observed with half-lives of some protein levels as low as 10 years.

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