Divergent expression of bacterial wall sensing Toll-like receptors 2 and 4 in colorectal cancer.

World J Gastroenterol · 2017 · PMC5514649 · PMID 28765705

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

showed a trendP = 0.074so close (0.05 < p ≤ 0.1)

In a stage-adjusted Cox model, strong TLR4 expression showed a trend to association with a better prognosis; in the tumour front, the HR for overall survival was 1.8 ( P = 0.074, 95%CI: 0.9-3.3), and in the tumour bulk, it was 1.7 ( P = 0.059, 95%CI: 1.0-3.1).

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did not reach statistical significanceno p-value reported

Tumour bulk showed the same pattern, and in lymph node metastasis, the overall survival benefit was as high as 50%, but likely because of our small sample size, these clinically highly notable differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.