Interestingly, a significant trend effect was seen, with FoG frequency being lowest with absence of both pathological conditions, intermediate in subjects with single extranigral pathological condition and highest with combined neocortical cholinopathy and amyloidopathy.
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Deficits in cholinergic neurotransmission and their clinical correlates in Parkinson's disease.
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The sentences
The absolute duration of onset and end-of-dose dyskinesias tended to be shorter with either drugs, but this failed to reach statistical significance.