Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease.

Although each of these associations was nominally significant, neither reached the prespecified Bonferroni-adjusted P value.

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Although the associations of p.A1369S with stroke, heart failure, or peripheral vascular disease did not reach statistical significance, effects were directionally consistent with protection without evidence for significant heterogeneity across phenotypes ( P heterogeneity = 0.74) ( Fig. 3 ).

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