Intrinsic Plasma Cell Differentiation Defects in B Cell Expansion with NF-κB and T Cell Anergy Patient B Cells.

Although BENTA B cells showed a trend toward increased EdU incorporation for some stimuli, we found no significant differences in proliferation of activated control and BENTA B cells in response to any stimuli tested (Figure 2 B).

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However, we observed a clear trend of reduced IgG ASC in BENTA B cell cultures stimulated with SAC + IL-2 and our anti-IgM/anti-CD40/IL-21/IL-2 cocktail (Figures 5 A,C).

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