Extra-virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy.

Although we observed a reduction in the A β 1‐42 RIPA–soluble and formic acid soluble fractions in brain homogenates from the EVOO‐treated mice, in both cases the differences failed to reach statistical significance (Fig. 2 A and B).

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Compared to control, the EVOO group had an increased freezing response activity in the cued recall phase, but the difference did not reach statistical significance (Fig. 1 C).

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