Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation.

Neuromolecular Med · 2017 · PMC5570801 · PMID 28623611

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hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 1 × 10 −6actually significant

One-way ANOVA for repeated measures followed by Tukey post hoc test revealed a highly significant difference ( p < 1 × 10 −6 ) between Fe-treated animals versus the other three groups (Fig. 1 b).

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did not reach statistical significanceno p-value reported

Furthermore, there was a trend for more aggregation in A53T animals supplemented with Fe, but the results did not reach statistical significance.

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showed a trendno p-value reported

In the hippocampus, again the A53T/DFP/Veh group showed a trend to less aggregation, while the A53T/Fe and A53T/DFP/Fe groups showed trends to more aggregation ( p = 0.065) (Fig. 5 b).

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