Increased p16 and p53 protein expression predicts poor prognosis in mucosal melanoma.

Oncotarget · 2017 · PMC5581105 · PMID 28881806

Europe PMC DOI

hedged sentences

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

showed a trendp=0.081so close (0.05 < p ≤ 0.1)

Accordingly, patients with high p16 showed a trend toward poor one-year survival rates (HR, 2.78, 95%CI, 0.88-8.73, p=0.081) and two-year (HR, 1.69, 95%CI, 0.79-3.66, p=0.181).

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did not reach statistical significanceno p-value reported

For p16 this was limited to reduced overall, three year survival, and, for p53 it was reduced to one and two year survival (with a trend towards worse three year survival that did not reach statistical significance).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.