Set8 expression showed a trend of increased expression following BPA exposure, with an average of 1.7-fold increase (25 nM), approaching statistical significance.
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Differential effect of estradiol and bisphenol A on <i>Set8</i> and <i>Sirt1</i> expression in prostate cancer.
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Treatment with ICI reversed this effect (average expression was 1.1), although it did not reach statistical significance ( Fig. 4 B).