Other miRNAs approaching significance with log2 fold changes up- or downregulation by greater than 1 included miR-10a, miR-133b, miR-138, miR-150, miR-155, miR-212, miR-362-3p, miR-518e, and miR-885-5p.
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IκK-16 decreases miRNA-155 expression and attenuates the human monocyte inflammatory response.
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Other suppressed genes that did not reach statistical significance included NFKBIE, CD14, IKBKE, MAPK10, and REL. miR-155 is upregulated in the impaired monocyte Differences in miRNA expression between naïve and impaired monocytes were initially determined by miRNA screening.